Febrile non-hemolytic transfusion reactions get no respect! Clinicians treat them as a nuisance, and so do most blood bankers! Dr. Christine Cserti-Gazdewich suggests they may be a bigger deal than we think.Febrile reactions are pretty common (maybe not as often as in years past, but still…). They are a “diagnosis of exclusion,” meaning they are what is left behind after you have ruled out other stuff. As a result, their impact is often minimized. Christine Cserti-Gazdewich is senior author on a 2017 paper that outlines the true cost of febrile reactions. While the monetary figures may not blow you away, the overall impact is significant! Christine takes us through a great discussion of how to recognize, understand, classify, and evaluate febrile reactions and appreciate their impact on patients.
About My Guest:
Christine Cserti-Gazdewich trained in internal medicine and hematology in Toronto, and in Transfusion Medicine at the Harvard Joint Program in Boston. She is an Assistant Professor at the University of Toronto, and a Transfusion Medicine specialist and a clinical hematologist at the University Health Network (UHN). She also provides remote associate medical directorship to other Ontario hospital transfusion services. Christine’s local work focuses on transfusion immunohematology and hemovigilance, with interests in the hematology and hemotherapy of severe anemia in sub-Saharan Africa. She was an investigator in the “TOTAL RCT” (on blood storage effects in the transfusion of profound pediatric anemia), and in a clinical field trial examining host blood group relationships and survivorship under Plasmodium falciparum malaria selection pressure.
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DISCLAIMER: The opinions expressed on this episode are those of my guest and I alone, and do not reflect those of the organizations with which either of us is affiliated. Neither Dr. Cserti-Gazdewich nor I have any relevant financial disclosures.