Cryoprecipitate is easily the most misunderstood blood product, and lots of confusion surrounds it (not just among clinical folks!). Dr. Chaffin and co-host Dr. Heidi Shafi give you five “Essentials” of cryoprecipitate to set record straight!
The blood product “cryoprecipitate,” prepared by slow-thawing fresh frozen plasma, is declining in use around the world but seems to be increasing in use in the United States. This discussion will help dispel myths and misunderstandings about the most misunderstood blood component. Dr. Chaffin discusses how cryo is made, what is in it, how it is prepared for transfusion, how it is used, and finally, what the future looks like for the use of cryo.
DISCLAIMER: The opinions expressed on this episode are those of my co-host and I alone, and do not reflect those of the organizations with which either of us is affiliated. Neither Dr. Shafi nor I have any relevant financial disclosures.
The images below courtesy of LifeStream Blood Bank.
- Callum J et al. Cryoprecipitate: The current state of knowledge. Transf Med Rev 2009; 23:177-188.
- Nascimento B et al. Cryoprecipitate Therapy. Br J Anaesth 2014; 113(6):922-34.
- Levy JH et al. Fibrinogen as a therapeutic target for bleeding: a review of critical levels and replacement therapy. Transfusion 2014;54:1389-1405.