Drugs that lead to immune red cell hemolysis can be super-sneaky! They can be overlooked, but a vigilant blood banker always considers them when evaluating mysterious reactions and especially, unexplained hemolysis. Pat Arndt give us great tips to “sleuth” out these challenging cases!
DISCLAIMER: The opinions expressed on this episode are those of my guest and I alone, and are not those of the organizations with which either of us is affiliated. Neither Pat nor I have any relevant financial disclosures.
The images below are generously provided by Patricia Arndt.
- Arndt PA. Sally Frank Memorial Award and Lectureship* Drug-induced immune hemolytic anemia: the last 30 years of changes. Immunohematology 2014;30:44-54.
- Garratty G and Arndt PA. Drugs that have been shown to cause drug- induced immune hemolytic anemia or positive direct antiglobulin tests: some interesting findings since 2007. Immunohematology 2014;30:66-79.
- Leger RM, Arndt PA, and Garratty G. How we investigate drug-induced immune hemolytic anemia. Immunohematology 2014;30:85-94.
- Petz LD et al. Cimetidine-induced hemolytic anemia: the fallacy of clinical associations. J Clin Gastroenterol 1983;5:405-9.
Note: The first three articles listed above are available for free from the American Red Cross’ “Immunohematology” journal site.