Dr. Curtis

Dr. Brian Curtis

Dr. Brian Curtis from BloodCenter of Wisconsin joins me to discuss Neonatal Alloimmune Thrombocytopenia (NAIT).

Neonatal alloimmune thrombocytopenia (NAIT), the disease with many names, continues to confound blood bankers everywhere! The conversation goes like this: “This baby has a low platelet count…is it NAIT?” Answer: “Ummmm….” I’m not meaning to offend anyone in transfusion service-world, because obviously, there are experts on this topic out there! Fortunately for us, I happen to have interviewed one of those experts for this podcast episode! Dr. Brian Curtis oversees one of the the world’s foremost labs for platelet antigen/antibody testing, and he explains how to take the right steps to find the answer, both in the real world and the exam world.

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DISCLAIMER: The opinions expressed on this episode are those of my guest and I alone, and do not reflect those of the organizations with which either of us is affiliated. Dr. Curtis wants you to know that he has done research for Prophylix, the Norwegian company mentioned in the episode that is attempting to bring a medication to market to prevent NAIT. I (Dr. Chaffin) have no relevant disclosures.

The images below are generously provided by Dr. Curtis.

Curtis Slide 1 - General Description of NAIT
Curtis Slide 2 - Clinical Features of NAIT
Curtis Slide 3 - NAIT Pathogenesis
Curtis Slide 4 - Proportion of worked up cases with antibodies
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