Thawed Plasma

A previously frozen plasma product that has been thawed in preparation for transfusion for more than 24 hours and less than 5 days. Many products can be relabeled as Thawed Plasma, including:

When one of the above products is thawed for transfusion, it must be stored in the refrigerator (1-6C) if not transfused immediately. The product technically has only a 24 hour shelf life, but the “”Circular of Information” describes a pathway to avoid discarding an unused product at the end of the 24 hours. The products above may be re-labeled as “Thawed Plasma” (note the CAPITAL “T” and “P”) and stored under the same conditions as before (i.e., 1-6C) for up to 5 days after thawing (technically, Cryo-reduced plasma must be re-labeled as “Thawed Plasma Cryoprecipitate Reduced,” but the principle is the same). Most facilities use Thawed Plasma for exactly the same indications as the original component, with the possible exception that, due to the documented decrease in factor VIII and to a lesser extent factors V and protein S, some will limit its use in cases of consumptive coagulopathies like DIC. This product is not recognized by the FDA, but is also not prohibited by FDA! Transfusion services use this shelf life extension to keep a small supply of already thawed plasma for urgent situations, with less risk of expiration.

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