A List of Commonly Used Terms in Blood Banking


The so-called “John Milton Hagen” system is composed of multiple very high incidence antigens based on a very common membrane protein called “semaphorin 7A” (which is widely present but has an unknown function). Antibodies in this system are found on occasion in reference laboratories, and are usually not enormously important in that they do not typically cause significant hemolysis or hemolytic disease of the fetus/newborn.

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