Rh Blood Group System Quiz

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1. Name the three genes responsible for the production of Rh antigens.
2. Which of the following is TRUE regarding the weak D phenotype?
3. Which of the following red blood cell abnormalities is associated with the Rhnull phenotype?
4. A patient has the following Rh phenotype:

   D:+ C:+ c:+ E:+ e:+

   What is her most likely Rh genotype?
5. A Caucasian patient has the following Rh phenotype:

   D:+ C:+ c:+ E:- e:+

   Which of the following is his most likely Rh genotype?
6. An African-American patient has the following Rh phenotype:

   D:+ C:+ c:+ E:+ e:+ f:–

   Which of the following is her most likely Rh genotype?
7. An African-American male potential blood recipient has the following Rh phenotype:

   D:+ C:+ E:– c:+ e:+

   Which of the following is his most likely genotype?
8. A 35 year old O-negative male trauma patient receives a transfusion of two units of O-positive red blood cells before his blood type is known. After his typing is completed, he is switched to O-negative and he receives 6 additional type-specific RBC units. He survives and is transferred to the surgical ICU. Which of the following is TRUE regarding his situation?
9. What percentage of blood specimens derived from those of European descent will have a positive agglutination result with the anti-c reagent?
10. Which alloantibody is most likely to be produced if a patient that has the Rh genotype of R1R1 is transfused with red blood cells that have an Rh genotype of R0R0?
11. A 63 year old male presents with a positive antibody screen and clinical and serologic findings consistent with warm autoimmune hemolytic anemia. In addition, the reference lab technologist also identifies an antibody that reacts stronger when the test RBCs are D-positive. The supervisor suggests the technologist consider anti-LWa in addition to anti-D. Which of the following TWO techniques will MOST assist in differentiating between these two antibodies?
12. In which of the following groups is Weak D testing required if the initial D typing results appear negative?
13. Which of the following is TRUE about Anti-D?
14. Anti-G will react with red blood cells of each of the following phenotypes except:
15. If a patient had a positive direct antiglobulin test (DAT) with Anti-IgG, what would happen if you performed a Weak D test on the patient cells?

 

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