Glossary

A List of Commonly Used Terms in Blood Banking

ULvWF

One of my favorite abbreviations in the whole world! ULvWF stands for “ultra-large von Willebrand factor” (but in my mind, I will always think of it as “unusually large vWF”) In most cases of thrombotic thrombocytopenic purpura (TTP), deficiencies of the ADAMTS13 enzyme lead to a lack of normal trimming of vWF molecules into smaller fragments. The ULvWF multimers attract platelets, which form thrombi in small blood vessels and lead to vascular and red blood cell damage (both important parts of the pathophysiology of TTP).

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